Sentence examples for pathway of death from inspiring English sources

"You can see the common pathway of death and suffering is heart failure," said Prof Yacoub.

The scientists also discovered Pseudo-nitzschia australis, domoic acid, and traces of anchovies in sea lion feces--damning evidence, they say, of a pathway of death from algae to anchovies to sea lions.

If latently infected CD4 T cells that reactivate HIV do not die, then it is possible that the Casp8p41 pathway of death is not operational in such cells.

These results suggest that USP17 subfamily proteins containing hyaluronan and RNA binding motifs are involved in signaling pathway of death for tumorigenic cells.

It is known that LMP can lead to both apoptosis and necrosis, depending on the extent of LMP; necrosis appears to be the dominant pathway of death in the setting of massive LMP, whereas partial LMP drives apoptotic cell death.

An additional pathway of death receptor-induced cell death may proceed through the mitochondrial pathway by activating the Bcl-2 pro-apoptotic protein Bid [ 24, 25], which is cleaved by caspase 8 following death receptor ligation.

In the extrinsic pathway, activation of death receptors such as Fas and tumor necrosis factor-alpha (TNFR) leads to activation of downstream caspases to induce apoptosis [ 32].

Cellular FLICE inhibitory protein (c-FLIP) is an endogenous inhibitor of the caspase-8 pro-apoptotic signaling pathway downstream of death receptors.

Active caspase-9 was present in splenic lymphocytes with apoptotic features, suggesting a mitochondrial-mediated pathway of cell death, although evidence indicates that apoptotic cell death in patients with sepsis can also proceed by the death receptor pathway (4 ).

Blocking fangchinoline-induced autophagy process would alter the pathway of cell death leading to apoptosis; thus cell death was an irreversible process induced by fangchinoline [ 34].

The intrinsic mitochondrial pathway of cell death includes cytochrome c release and activation of caspase-3 and is the major death pathway involved in MPP+-induced toxicity.