Sentence examples for pathway of damage from inspiring English sources

From our previous work showing that RAD18 defines a post-replicative pathway of damage bypass [3], these data suggest that WRN too would act behind the replication fork.

The researchers acknowledge that much more work needs to be done addressing variables such as sex, age, race, geographic setting, pathway of damage, and affected body system.

Genetic evidence in yeast has implicated this modification in an error-free pathway of damage avoidance that likely involves template switching, but the mechanistic aspects of the reaction are unexplored (Hoege et al. 2002; Zhang and Lawrence 2005).

We have used single-molecule techniques to examine quantitatively the cellular effects of adding well characterized Aβ oligomers to primary hippocampal cells and hence determine the initial pathway of damage.

We would hypothesize that induction of transcription of the genes encoding ASPA, hemopexin, parvalbumin and creatine kinase are part of a pathway of damage triggered repair mechanisms, responding to esfenvalerate insult.

The two modifications label PCNA for alternative functions: mono-ubiquitylation activates translesion synthesis through damage-tolerant DNA polymerases (Stelter and Ulrich, 2003; Kannouche et al, 2004; Watanabe et al, 2004), and poly-ubiquitylation is required for an error-free pathway of damage avoidance possibly involving a template switch (Hoege et al, 2002; Zhang and Lawrence, 2005).

Analysis of global transcriptional and phenotypic responses in the yeast S. cerevisiae provides means to identify pathways of damage recovery upon toxic exposure.

Although OA is a heterogeneous disease with multiple pathways of varied etiologies leading to a common endpoint of joint damage, we propose a "bone adaptation" paradigm with a common final pathway of cartilage damage in both primary and secondary knee OA.

This indicates a selective pathway of oxidative damage to lipids, and although membrane-associated proteins may also be targets for oxidative damage of nC60, the cytosolic proteins may not be affected.

A combination of a temperature spike and electron/hole interactions may be a dominant pathway of DNA damage.

A common pathway of oxidative damage centers on tyrosine with the generation of 3,4-dihydroxyphenylalanine (l-dopa).