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Although no single evaluation provided enough information to enable us to describe an explicit pathway of activities to outputs and outcomes, it was possible to link common indicators across evaluations.
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10.7554/eLife.01008.015 Figure 5. diVCA constructs differ in the rate but not the pathway of activity in stimulating branch formation.
The study showed that astrocytes could in fact respond to extracellular neurotransmitters such as those released by neurons via a signalling pathway that could potentially be used for physiological glial communication although more research is required to elucidate the exact pathways of activity.
This implies some level of plasticity or compensation, or of independent pathways of activity for menin and p53.
The ligand dependence is revealed when there exist two depletion pathway of the activity, one of which exhibits a non-first order property (Fig. 10).
These fascinating discoveries raise many questions regarding its regulation pathway, mechanisms of activity and advances in miR-based therapeutic strategies.
Figure 3 shows, for each care pathway, the number of activities present among the 10 activities characterizing each development phase (see Table 6 for detailed activities).
There are no accepted standards for evaluation of pathway activities or simulation of flow propagation events in pathways, and the results of different software are difficult to compare.
Assessment of pathway activities is crucial for determining which pathways play roles in disease versus normal conditions.
In addition, predictions of pathway activities in a third independent data set provided further confirmation for the patterns of pathway activity typical of a given intrinsic subtype [see Additional data file 1].
Antioxidant and pro-oxidant pathophysiological pathways of physical activity need to be elucidated, apparently, beneficial effects on oxidative stress and health are obtained when regular moderate training is practiced [3].
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