Sentence examples for pathway of action from inspiring English sources

Compared to the traditional system of drug design and discovery, that involves blind testing of different chemicals in vitro and in vivo in cultured cells and animals, rational approach is totally based on the knowledge of the target and the pathway of action.

In stage 2, the actual pathway of action remains unknown [19].

Following the identification of a common pathway of action of ASA/SA and BoxA, we tested the efficacy of BoxA in vivo.

Our findings indicate that these effects may be the result of simultaneous inhibition of JAK2 and BETs by TG101209 (dual pathway of action).

We utilised a pathway of action to understand the working of communication technologies in the diabetes healthcare context [ 15] coupled with several forms of communication technologies [ 18, 19] or other self-management interventions [ 20].

The concentrations at which XEs are believed to be mechanistically active have largely been determined by assaying for the transcriptional activity of these compounds via the well-established nuclear pathway of action for steroids.

Further, by identifying susceptibility genes and their pathways of action, it may be possible to identify previously unsuspected carcinogens.

The objective of this paper is to characterize CHW attributes and pathways of action using adapted measures, develop a scale using these measures, and explore how findings can inform future CHW research and practice.

To our knowledge, our study is one of the first to differentiate two pathways of action for visfatin-induced anorexia, hypothermia, and hypoactivity.

Delineating the pathways of action of these molecules in older people is therefore important.

Further studies are required to fully elucidate the pathways of action.