Exact(1)
Hence, this knowledgebase is deposited into a public repository endowed with a pathway navigator, which facilitates browsing through the nodes and entities of the uploaded pathway.
Similar(59)
Different visualization tools can yield different and complementary biological information; Fig. 4 shows three alternative visualizations of MAPK3 using pathway databases and PPIs in NAViGaTOR.
For example, NAViGaTOR uses web services to access pathway data from KEGG, Reactome, Pathway Commons (Cerami et al. 2011) and Wiki pathways (Pico et al. 2008), protein interactions from the IMEx consortium (Orchard et al. 2007), and protein interactions and gene associations via i-HOP (Hoffmann and Valencia 2005) or STRING.
Using NAViGaTOR ver. 2.1.13 to display the microRNA:pathway interactions from the KEGG 3+DB study, we laid out the micronome roadmap to identify universe and intra-pathway microRNAs.
10– 13 Recently, we 3, 4 and Calderwood's group 14 have shown that Hsp90 also acted as an excellent navigator for associated antigens to enter the cross-presentation pathway in the murine system.
The public databases are T2D-Db (available at http://t2ddb.ibab.ac.in/home.shtml), HuGe Navigator [25] and the curated database of the Ingenuity Pathway Analysis software.
From these non-redundant interaction data, disease-protein network (DPN), disease-disease network (DDN), common pathway network (CPN) and disease-biomarker network (DBN) were created and visualized using Cytoscape version 2.7.0 and NAViGaTOR version 2.1software.
Using NAViGaTOR to produce interaction networks implicating microRNAs in literature-based, KEGG-based and Reactome-based pathways, we find these signalling pathway networks have significantly more microRNA involvement compared to chance (p<0.05), suggesting microRNAs co-target many genes in a given pathway.
HEALTH navigator?
The British navigator Lieut.
"Shared pathway".
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Justyna Jupowicz-Kozak
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