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Enrichment analysis in pathway maps for differentially expressed genes.
Biological pathway maps are highly relevant tools for many tasks in molecular biology.
KEGG pathway maps for (a) fatty acid degradation pathway (ko00071) and (b) PPARα signaling pathway (ko03320 49.
Block-diagrams, commonly used in the engineering sciences, are introduced and compared to pathway maps.
We create templates for function classification and suggest that they can extend signaling pathway maps.
Several pathway maps are already commonly used by biologists.
Canonical pathway maps represent a set of about 500 signaling and metabolic maps covering human biology.
Results are presented as pathway maps with overlaying gene-expression data.
Pathway maps were edited in Mapeditor (GeneGo Inc., St. Joseph, MI, USA) version 2.1.0.
Many pathway maps have been provided online as part of public pathway databases.
We defined both pathway maps as "autonomous pathway maps".
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