Sentence examples for pathway insights from inspiring English sources

Bindea, G., Galon, J. & Mlecnik, B. CluePedia Cytoscape plugin: pathway insights using integrated experimental and in silico data.

Because individual tumors often have unique defects in the DNA damage response (DDR) pathway, insights into the basic mechanisms by which cells repair different DNA lesions could also guide individual therapy.

Because photolyase is evolutionarily related to other FAD-binding proteins, such as cryptochromes, which share a conserved Trp hole-hopping pathway, insights regarding photolyase may be directly applicable to a wide variety of proteins.

Author's response: As the article also discussed much about the ancient function of RB-E2F pathway, we still kept the title "The ancient function of RB-E2F Pathway: insights from its evolutionary history" The paper is difficult to understand and should be clarified, in particular the fact that some duplications are lineage-specific and other are older.

Taniguchi C. M., Emanuelli, B. & Kahn, C.R. Critical nodes in signalling pathways: insights into insulin action.

Given the molecular conservation of developmental genes and pathways, insights from cichlids are applicable to human facial variation and disease.

As carcinogens are increasingly recognized to affect multiple molecular mechanisms and thus multiple cellular pathways, insights into these mechanisms could inform new predictive approaches, such as predictive in vitro assays, and allow for the development of specific, mechanism-based human biomarkers.

Tasaki, T. & Kwon, Y. T. The mammalian N-end rule pathway: new insights into its components and physiological roles.

Popiolek-Barczyk, K. & Mika, J. Targeting the Microglial Signaling Pathways: New Insights in the Modulation of Neuropathic Pain.

Despite the extreme genetic heterogeneity, many genes converge in functional pathways, giving insights into the underlying pathophysiology and providing therapeutic targets.

We applied these synthetic controllers to the systematic titration of flux through the ergosterol biosynthesis pathway, providing insight into endogenous control strategies and highlighting the utility of this control module library for manipulating and probing biological systems.