Sentence examples for pathway implications from inspiring English sources

These multiple ET-axis pathway implications may explain its various impairments of normal cellular integrity in case of an aberrant shift from balanced to imbalanced EDN signalling.

Another key cellular stress response pathway having implications in basal tolerance to azoles is the protein kinase C (PKC) mediated cell wall integrity pathway (CWI).

The stilted nature of the VR pathway had implications for the timing of SSVR.

Overall, our findings emphasize the importance of respiratory substrates in regulating S-nitrosylation through a thiol-dependent pathway, with implications for mitochondrial bioenergetics and mitochondrion-driven apoptosis.

Thus, understanding the mechanisms that control NCOA4 abundance could help unravel the physiological underpinnings of flux through the ferritinophagy pathway, with implications for understanding iron utilization.

Thus, a better understanding of the BER pathway has implications in the potentiation of the therapeutic effects of DNA-damaging agents.

It describes the case and control identification and selection methods that were ultimately decided for PERCH, and the options considered along the decision pathway, the implications and tradeoffs for each, and rationale for the final decisions.

The same effect of prohibitin in the levels of glutamate may have a complete different outcome in animals with an intact or with a compromised IIS pathway, with implications on the longevity of the worms.

These findings emphasize the importance of respiratory substrates in regulating S-nitrosylation through a thiol-dependent (GSH and/or thioredoxin) pathway, with implications for mitochondrial bioenergetics and mitochondrion-driven apoptosis.

The delayed progression of the autophagic pathway has implications for organelle turnover in this disease and although accumulation of subunit c of mitochondrial CV is specifically associated with BD, it appears that it may be a secondary effect due to impaired autophagy in this disease state.

These results would suggest that at least two different (and potentially conserved) PDGF/VEGF signaling pathways are operating during medusae development and that the alteration of these pathways has implications in medusae evolution.