Sentence examples for pathway impacts from inspiring English sources

Inhibition of the enzyme EPSPS and disruption of the shikimate pathway impacts protein synthesis and production of phenolics, including defence molecules, lignin derivatives, and salicylic acid [28].

This review focuses on the progress in our understanding of how manipulation of the MEP pathway impacts carotenoid biosynthesis and on the discoveries underlining the central importance of coordinating the supply of MEP-derived precursors with the biosynthesis of carotenoids and other derived isoprenoids.

An interesting and topical aspect is the extent to which individual variation in the autophagy pathway impacts healthy aging.

Ezh2, downstream of the Egfr-ras-raf pathway, impacts DNA methylation, promotes EMT and is associated with poor prognosis in CRC [ 18, 19].

Previous data reported by us [ 4] and by others [ 5] have suggested that the transsulfuration pathway impacts on the rate of aging, probably by regulating intracellular availability of methionine.

Furthermore, immune 'manipulations' probably have more complex effects on innate immune activation and other factors that could influence AD pathologies than what are currently being surveyed, and thus a broader approach may be needed to understand how manipulations of a given innate immune pathway impacts AD.

Via this pathway, impact among economic actors may be generated, although impacts may not have the aimed for high degree of dispersion in the current still small scale experimental phase.

Affected KEGG pathways were ranked in order of classical p-values as well as gamma corrected p-values, which refers to pathway impact analysis or a measure of the probability of a pathway being significantly regulated.

To understand the extent to which the Let7 pathway defines C5 tumours, we used a recently described signalling pathway impact analysis (SPIA) [34] to probe other signalling pathway dependencies.

Including semantics also opens new possibilities for analysis in Cytoscape, for example the signaling pathway impact factor analysis method [17], which can use the distinction between activation or inhibition interactions.

To assess perturbation of signaling pathways we applied SPIA (Signaling Pathway Impact Analysis [ 21]).