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The discovery that EFI-501083 can fulfill the role of the long-hypothesized phosphatase in the riboflavin biosynthesis pathway illuminates the potential of this method for new biological discovery.
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Twenty-four older adults (half identified at risk for falls) experienced three lighting conditions: pathway illuminated by 1) general ceiling-mounted fixtures, 2) conventional plug-in night lights and 3) plug-in night lights supplemented by laser lines outlining the pathway.
Understanding the logic of plant natural product biosynthesis is important for three reasons: it guides the search for new natural products and pathways, illuminates the function of existing pathways in the context of host biology, and builds an enabling 'parts list' for plant and microbial metabolic engineering.
The majority of these genetic associations are near genes that map to critical immunoregulatory pathways, illuminating genetic effects that are shared across multiple autoimmune diseases and other genetic effects that are restricted to only a few (1).
The pathway was illuminated by quick bursts of flashlights.
These data add to the characterization of the spinosyn biosynthetic pathway and illuminate the role of auxiliary proteins in the activation of GTs.
Another protein modification pathway that was illuminated by the screen is that of an ubiquitin-like modification, SUMO.
This illuminates pathways involved in ciliary specialization and the molecular mechanism of transcription factors that regulate them.
Luminescent nanostructures serve as an essential tool for illuminating the pathway of drug or gene delivery in biomedical systems.
In February, declaring that it's time to "accelerate and illuminate the pathway from microscope to market," U.S. Department of Health and Human Services Secretary Kathleen Sebelius announced a landmark collaboration between FDA and the National Institutes of Health in regulatory science.
This study illuminates the pathways involved in the response to CG-1521 in yeast and provides incentives to understand the mechanisms of HDAC inhibitors in cancer cells.
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CEO of Professional Science Editing for Scientists @ prosciediting.com