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Pathway group 2 comprises all impact pathways along geological faults.
2- Interferon and growth factors group 3- Leptin Pathway group.
Pathway group 1 refers to potential (pollutant) discharges and migration along wells, i.e. to artificial underground pathways.
Pathway group 0 refers to (pollutant) discharges that occur directly at the ground surface, and especially in handling of fracking fluids (transport, storage, etc).
Pathway group 3 comprises extensive rise, as well as lateral spreading, of gases and fluids through geological strata (for example, via an aquifer), without preferred pathways similar to those described for pathway groups 1 and 2. Impact pathways in pathway group 3 depend primarily on the prevailing geological and hydrogeological conditions.
In case of substances entering groundwater from the surface (pathway group 0, e.g. accidents during transport and preparation of fracking fluids), the relevant substance concentration for the assessment is the concentration at the groundwater surface (see page water).
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Observed mean times were not only slower among the local participation groups, when compared with talent pathway groups, but also more variable (Fig. 3).
By analogy, in the case of a possible release from the fracking horizon (and related migration via pathway groups 1 through 3), the concentration at the base of the exploitable groundwater aquifer should be used in the assessment.
Table 1 shows the different pathway groups that classify different phenotypes.
The overlapping KEGG pathway groups possessed a strong signaling phenotype as typified by the Jak-STAT and MAPK signaling pathways.
According to the gene enrichment analysis for the KEGG pathway, the three most enriched pathways identified are related to brain function, i.e., the pathway groups "Neuroactive ligand-receptor interaction", "Long-term depression", and "Neurodegenerative disorders" (Table 6).
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