Sentence examples for pathway feedback from inspiring English sources
Finally, recent studies have demonstrated the presence of a PKM2-ROS-pentose phosphate pathway feedback loop in human cells, further confirming the role of PKM2 up-regulation in redox balance [14].
In particular, we assessed the molecular mechanisms of pathway feedback and cross-talk.
Mammalian target of rapamycin inhibitors possess modest activity against STS; however, resistance develops via MAPK pathway feedback activation.
It will be of interest to explore whether CRC patients with low SOCS6 levels show elevated YAP/AREG/EGFR pathway feedback activity.
The relation may in some cases be less straightforward, probably due to the complexity of gene regulation, including pathway feedback loops.
The three most significantly affected signalling pathways between UKF-NB-3 and UKF-NB-3rNutlin10 μ M cells were 'p53 pathway feedback loops 2'WntWnt signalling', and 'p53 pathway'.
Such synthesis must take into account the dynamic state of protein post-translational modifications and protein protein or protein DNA/RNA interactions, cross-talk between signal pathways, feedback regulation within cells, between cells, and between tissues.
Early reports suggested that it was generated by horizontal cells [7], [8] which appear to act through two pathways: feedback inhibition to photoreceptors [9], [10] and feedforward inhibition to bipolar cells [11], [12].
The neural systems regulating the effect of the surround on the classical receptive field (CRF) are complex, but are understood to involve both feedforward responses from earlier sites in the visual pathways, feedback responses from extrastriate visual cortices, as well as lateral inhibition within primary visual cortex (for review see: [31], [32]).
Many reports have shown that cancer cells can exploit redundancies in pathways, feedback loops, and crosstalk in order to survive despite the administration of specific drug treatments [ 34].
Glucose repression is a complex and intertwined regulatory system, with extensive cross-talk among pathways, feedback loops and different levels of regulation responding at different time scales.
