Exact(17)
Microarray data was LOWESS normalized using ArrayTrack (http://www.fda.gov/ScienceResearch/BioinformaticsTools/Arraytrack/default.htm) and pathway analysed using the Gene Set Analysis Toolkit, KEGG pathway feature (http://bioinfo.vanderbilt.edu/webgestalt).edu/webgestalt
(c) The third is the SVM-based pathway feature (SPF) method.
We would use a better way to represent the KEGG pathway feature set.
The classifier based on this procedure was designated as the random pathway feature (RPF) method.
Moreover, the Pathway feature increased the dimensions of our feature space rather than refined our predictors.
(b) The second is denoted as the GSEA Pathway Feature (GPF) Method.
Similar(43)
Platelet-activating factor (PAF), a metabolite of arachidonic acid pathway, features prominently in cell proliferation, migration and angiogenesis.
The model permits investigation of various pathway features, such as the effects of changing levels of signalling proteins at specific regulatory steps.
Heat shock generates misfolded or aggregated proteins that trigger heat shock response pathway featuring the induced synthesis of a set of evolutionarily conserved heat shock proteins [31].
(9) Independent models with pathway features (Indep. Path).: This baseline incorporates the pathway information from the pathway vectors as features.
In comparison, it was 60% using the same number of randomly selected pathway features (RPF) as the number of pathway features in GPF.
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