Sentence examples for pathway execution from inspiring English sources
Block of cell cycle in G2/M phase and subsequent inhibition of primary cilia formation may negatively influence the Shh pathway execution.
There are two pathways currently proposed to play major roles in regulating apoptosis in mammalian cells: a pathway mediated by death receptor (extrinsic pathway; execution by caspase-8) and a pathway mediated by mitochondria (intrinsic pathway; execution by caspase-9) [ 34].
Since Ulk3 is able to modulate the activity of Gli proteins and to interact with SU6668, the effects of SU6668 on the Shh pathway execution was tested in two Shh-responsive mouse cell lines C3H10T1/2 and 3T3-L1.
First, using two mouse cell lines and Ulk3 RNAi approach we have demonstrated that SU6668 inhibits the Shh pathway execution via Ulk3, as assessed by analyses of Gli1 and Ptch1 expression induced in a Gli2 dependent manner.
In addition to such a pathway, the execution of apoptosis also constitutes a caspase-independent pathway that is mediated by mitochondrial proteins AIF [ 20] and EndoG [ 21].
The mechanism of tRF action upon loading into Ago1 and Ago2 still remains unclear, but there are clues to suggest a miRNA-like pathway of execution.
In computer science, labeled transition systems (LTSs) are commonly used to represent possible computation pathways during execution of a program.
However, accumulating evidence now suggests that necrotic cell death may be accomplished by a set of signal transduction pathways and execution mechanisms (thus termed necroptosis) (Vandenabeele et al., 2010; Linkermann and Green, 2014).
The extrinsic and intrinsic pathways converge on the same execution pathway.
Analyzing the performance of individual steps in NetKO: the tableau algorithm generated 164,093 pathway fragments following execution of 708 of 761 iterations of the tableau algorithm during about 2 hours of execution.
Ookinetes that had been collected from gametocytaemic-blood following 18 h of culture were used to determine whether the execution pathway of NO-induced apoptosis involved the mitochondrion.
