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For the gemcitabine pathway, evidence of gene-set association varies considerably between the methods, with p-values for the pathway ranging from 0.002 for the PCA1.5 analysis to 0.341 for the PCA1 test.
STRING has three unique biological associations (gene fusion evidence, co-occurrence, and pathway evidence).
Unlike AraCyc or RiceCyc it summarizes the pathway evidence from the point of view of a single organelle.
The confidence values low, medium, high, and unknown indicate whether the MeSH assignment is based on direct (e.g. mutation in gene) or indirect (pathway component in disease gene pathway) evidence.
The list of early amino acids is plausible and derived from a combination of the Murchison meteorite, prebiotic synthesis and metabolic pathway evidence, which are the best available data and show remarkable consensus.
The inheritance of ATPS is complex, with multiple origins in the lineages that comprise the opisthokonts, different isoforms in chlorophytes and streptophytes, independent gene fusions in two species with other enzymes of the pathway, evidence of a eukaryote to prokaryote lateral gene transfer and two reversals of cellular location of host- and endosymbiont-originating enzymes.
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The decreased H2O dissociation was also found to affect the reaction pathway, evidenced by a shift in liquid product selectivity away from acetone and towards acetaldehyde.
This will activate caspase-8 that demonstrates the TNF receptor signaling pathway evidenced by increased caspase-8 mRNA expression (Fig. 10) in the hippocampus of adult rats.
Microalgal population that dominanted in Consortia-B appears to have opted the lipid storing metabolic pathway evidencing 2% lipid that can be converted to biodiesel.
Between 1 2 h, carbon flux occurred via the EMC pathway, evidenced by the accumulation of mesaconate, methylsuccinate, ethylmalonate, methylmalonate, methylmalonyl-CoA and propionyl-CoA (Figure 8, Table 1, summarized in Figure S1C), and cell growth occurred.
NeuroD1 has been identified as an essential regulator of the formation of hippocampus downstream of Wnt signalling pathway evidenced by a loss of hippocampal formation in NeuroD1 mutants.
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