Sentence examples for pathway drives from inspiring English sources

The activation of CD40 pathway drives microglia activation, brain inflammation, and oxidative damage and blood-brain barrier dysfunction.

In addition, the NO/cGMP/PKG pathway drives Notch signaling in PDGF-induced gliomas in vitro, and induces the side population phenotype in primary glioma cell cultures.

Deregulated activity of the Raf/MEK/ERK pathway drives uncontrolled tumor cell proliferation and survival, thus providing a rational therapeutic target for the treatment of many cancers.

Conversely, a very brief induction of Notch pathway drives the differentiation of post-mitotic cells into mature goblet cells via Hes5 expression [20].

Thus, it appears that stimulation of the cAMP/protein kinase A signaling pathway drives CRE-dependent MIE enhancer/promoter activation in quiescently infected cells; this suggests one potential mode of regulation in HCMV reactivation [19].

In addition to the spleen, BMP4 is also expressed in the fetal liver during development, and the BMP4 dependent stress erythropoiesis pathway drives the expansion of stress erythroid progenitors in the fetal liver[35].

Specifically, tRNAGluUUC promotes metastatic progression by directly enhancing EXOSC2 expression and enhancing GRIPAP1 constituting an "inducible" pathway driven by a tRNA.

These findings support the concept that cancer cells have high levels of ROS, and hence, have a strong reliance on the ROS stress-response pathway driven by NRF2.

However, by using density functional theory calculations, it has been shown that the whole set of coupled chemical reactions involved either in a Kolbe or Non-Kolbe pathway drive the overall mechanisms towards a thermodynamically favorable situation.

Although these two pathways may possibly raise a visual rivalry in the visual system, the pathway driven by the photoreceptor cell activation may overcome the pathway driven by activation of the ChR2-expressing RGC.

The PI3K-Akt-mTOR signaling pathway, driven or not by EGFR activation, negatively regulates autophagy [ 8].