The phrase "pathway direction" is a correct and usable phrase in written English.
You can use this phrase to describe the route or direction that someone is taking when attempting to reach a goal. For example, "John formulated a clear pathway direction to reach his financial goals."
The presence of cleavage consensus sites specific to adenain in the human cystatins could drive the adenain cystatin interaction predominantly in the substrate pathway direction.
Intriguingly, work in other organisms has shown that the equilibrium constants for these four reactions all favor the pentose phosphate pathway direction: ribulose-5-P isomerase (rpiA), ribulose-5-P epimerase (rpe), and both transketolase (tktA) reactions [66].
By reversal of the β-oxidation pathway [ 201] (see Section 'Altering the regulation or pathway direction' for details) and overexpression of an alcohol dehydrogenase, 330 mg l-1 n-alcohols with chain lengths of 5 to 10 carbon atoms were produced.
For example, the expression of genes encoding certain enzymes in gluconeogenesis suggests that the pathway direction where β-D-glucose 1,6-bisphosphate is converted in β-D-glucose 1,6-phosphate by fructose-1,6-phosphatase I (3.1.3.11) changed at 15 sai, either for energy storage or for providing glucose-6-phosphate for the pentose phosphate pathway for NADH production.
Therefore, it seems plausible that resistance development of PC3 cells may be accompanied by two different processes: (A) quantitative alterations of the integrin-expression level and (B) structural changes of the integrin molecules, leading to a switch of the intracellular pathway direction following short-term RAD001 treatment.
While there was some overlap, predictors typically varied by pathway and direction (e.g., using to not using vs. not using to using).
While these two genes are part of the same biochemical pathway the direction of reaction is unclear (Fig. 3).
The pathway effect directions of QPh3a, QPh4c, and QPh9a could not be determined based on the known QTL information except QG6.
Unlike genes annotated to inflammation/immune response pathways, the direction of differential gene expression for cholesterol/lipid metabolism and cell cycle genes was very clear (Figs. 2 and 4; Supporting Information, Tables S4 and S5).
Interestingly, while the female rats on the 20% CR diet showed a similar number of significantly altered pathways (48) the direction of the majority of pathway alterations was opposite to the pathways of the males.
Solid lines, possible pathways with directions indicated by arrows; dashed lines, impossible pathways in our studies.
