Sentence examples for pathway directed from inspiring English sources

In addition to HLA-G, one of its receptors, LILRB1/ILT2, is also found in MS brain tissue suggesting that HLA-G expression in MS brain is functionally relevant, possibly through an inhibitory feedback pathway directed at down regulating pro-inflammatory T cells.

A498 cell line experiments then allowed for confirmation of the concept in another cell line in an experiment that more closely mirrors the clinical situation in which a patient would be exposed to an antiangiogenic therapy and then have treatment held for awhile followed by subsequent treatment with the same or a similar VEGF pathway directed therapy.

Our senescence scoring approach allows us to look at senescence in a pathway directed way.

At present this seems unlikely, and major concern about pathway directed drugs remains.

These studies provide a compelling focus for pathway directed, rather than traditional tumour-type specific interventions.

We next wanted to know what signaling pathway directed CDC-42 membrane recruitment.

The Wnt signalling pathway directs aspects of embryogenesis and is thought to contribute to maintenance of certain stem cell populations.

One pathway directing various differentiation programs, including T-cell differentiation, is the Notch-signaling pathway.

Although we know much about the basal signaling pathway directing stomatal development [ 28, 29], we know little about how this pathway is modulated by environmental stimuli [ 28, 30].

These observations are consistent with the ascribed role of the hydroxylase on the pathway, directing the monolignol flux toward coniferyl and sinapyl alcohol formation.

We discuss evidence for how N-glycosylation impacts cell adhesion and cytoskeletal dynamics, as well as how the N-glycosylation pathway directs key oncogenic signaling pathways, such as the Wnt/β-catenin pathway (also known as the canonical Wnt pathway).