Implying cooperation between temporal and frontal areas that support these functions, DfM may be a sensitive index of integrity of cortical areas or neural pathways damaged by focal epilepsy.
Notwithstanding, future studies on visual pathway damage in MS should include additional cortical MRS voxel if possible.
DNA damage is detected by sensor proteins, which may overlap with specific repair pathway damage sensors.
Our hypothesis was that chromatic vision, similar to visual acuity, is generally impaired and positively correlated with the degree of motor impairment since visual pathway damage would probably affect other functions than spatial vision.
Of note, patients referred for kinetic visual field assessment were those usually with diagnoses of neurological and posterior visual pathway damage such as idiopathic intracranial hypertension, functional/malingering suspects, pituitary adenoma, stroke, and brain trauma injuries.
However, several questions remain concerning the cognitive impairment induced by DM: (1) Is the pathogenesis of the impairment caused by a sequence of phases, e.g. insulin signalling pathway damage, then impaired glucose metabolism, then inflammation?
This adds to the length of time required for the visual field assessment, particularly for patients with anterior visual pathway damage, but does show the value of starting the test with a standardised "template" and amending this further as indicated.
This metabolic pathway is damaged in breast cancer [ 70].
When cells experience irreversible ER stress, this pathway eliminates damaged cells by apoptosis.
Visual field loss following stroke has largely been attributed to cortical strokes in which the visual pathway is damaged.
