Sentence examples for pathway characterizes from inspiring English sources

The microsatellite instability (MSI) pathway characterizes about 15% of the colorectal cancers and is associated with diploid or near-diploid tumors and a defective MMR machinery, which is reflected as MSI in the tumor tissue.

57 The SHH pathway is crucial during neurodevelopment and hyperactivation of this signaling pathway characterizes a particular subgroup of medulloblastoma. 1 Although downregulation of RYR3 and RAB23 targets supported the effects of miR-367 overexpression observed in medulloblastoma cells, the downstream mechanisms underlying these miR-367-directed events remain to be elucidated.

Dear Editor, Autophagy is a lysosome-based degradation pathway, characterized by formation of a double-membrane vesicle named the autophagosome.

Shikimate Kinase is an enzyme of shikimate pathway, characterized as non-paralog, non-homolog, and essential for bacterial survival.

We have predicted a viable signalling pathway characterized in terms of the genes responsible that may be the PfPKB pathway recently elucidated in Plasmodium falciparum.

The mitochondria-mediated caspase activation pathway is a major apoptotic pathway characterized by mitochondrial outer membrane permeabilization (MOMP) and subsequent release of cytochrome c into the cytoplasm to activate caspases.

The apoptotic pathway typically attributed to this delayed death is the intrinsic/mitochondrial-mediated pathway characterized by a loss of mitochondrial potential, release of cytochrome c, and activation of caspase-9.

This suggests that the dense liana patches of NKMNP represent an alternative successional pathway characterized not by tree regeneration but rather by a stalled state of low-canopy liana dominance.

All the mutations lead to constitutive activation of the Wnt signalling pathway characterized by the formation of constitutive nuclear β-catenin/TCF complex.

In contrast, the mutant protein Δ7 followed an unproductive folding pathway characterized by the formation of intermediates displaying disulfide bonds accessible to DTT for all the chase times.

The foremost KEGG pathway identified by the GATHER analysis (Table 2) was the focal adhesion pathway, a pathway characterized by 210 genes, of which 41 overlapped with the human airway basal cell signature (Table S3).