Sentence examples for pathway bridge from inspiring English sources
Selective protein degradation pathways (UPS and MVB pathway) bridge the gap in amino acid recycling before an efficient autophagic response develops.
Pathway Bridge was defined as a subset of protein interactions network that consisted of clustering loop motifs with extremely high frequency occurring in cancer related processes than by chance.
Searched on the pathway bridge that has been enriched through prostate cancer pathways, the top 10 out of 88 forecasted paths were picked for further biological meaning verification (Supplementary Table 1.2).
Among the pathway bridge that consisted of protein nodes (dashed circles) and proteins' interactions (green lines), a shortest protein path with least DES cost was emphasized by red lines.
In order to see how the signature gene is enrolled in the ligand stimulation signal, a pathway bridge based multiobjective optimization approach (pbMOO) was designed and summarized, as shown in Figure 1.
Rather than traversing the entire protein interaction network with enormous nodes and edges, all the loop motifs were clustered as a "Pathway Bridge" between TGF β signaling pathway and cancer signaling pathway.
The method used in our study, that is deriving transfer function from the mathematic model of a pathway, bridges the two realms.
APPL proteins associate dynamically with endosomal membranes [20], and are proposed to function in an endosome-mediated signaling pathway bridging receptor activation at the cell surface with downstream nuclear signaling events [11].
The PCAF service is an innovative care pathway bridging the boundary between primary and secondary care.
As a follow-up, the intermediate pathway bridging MkRP and megakaryocytes was identified, and fully restricted unipotent megakaryocyte progenitors CD41+CD42b+LSK were characterized recently [ 27].
If changing condition of a protein A results in the upregulated or downregulated protein B, while A and B have neither direct interaction with each other nor indirect upstream and downstream relationship on any authentic signaling pathway, the underlying protein pathways for them could be detected on those MCs enriched pathway bridges.
