If an enzyme is missing or has diminished activity, the pathway becomes blocked, and the formation of the final product is deficient, resulting in disease.
The latter pathway becomes important when eating, and, as a result, there is considerable confusion in the use of the term taste, because odours from the food enter the nasal cavity at the same time as the taste buds are stimulated by food.
"Everything in that pathway becomes a potential target".
The intrinsic apoptotic pathway becomes activated when cells are critically damaged.
But at other clubs, that pathway becomes a dead end at 19".
At high mAb concentrations, the clearance approaches a first-order process where the FcRn mediated pathway is dominant and the nonlinear pathway becomes negligible.
As exponent α increases from 1.001 to 6, the dominant sub-network becomes denser, and the length of the pathway becomes longer.
It is argued that the diversity of these effects indicates that the mechanism by which the direct pathway becomes favoured does not involve any specific chemical functionality of the modifier.
Following overdose, and possibly also in extensive and ultrarapid metabolizers, this detoxification pathway becomes saturated, and, as a consequence, NAPQI accumulates (Dong et al. 2000; Hendrickson and Kenneth 2006; Borne 1995).
Here, we have instead concentrated on engineering the central carbon metabolism of Synechocystis such that (i) the PHB synthesis pathway becomes deregulated, and/or (ii) the levels of its substrate, acetyl-CoA, were increased.
l-arginine (l-arg), a semi-essential amino acid, depending on its metabolic pathway, becomes very essential in stress situations such as heatstroke, burns, sepsis, trauma, and wound healing.
