In each program, we selected one care pathway based on the managers' availability to participate in the study and the presence of a critical mass of potential respondents, with the aim of including pathways that were likely to be situated at different levels of advancement in their service integration process.
Targeting of a single oncogene or a specific signal transduction pathway based on the rationale of "oncogene addiction" is one of the basic approaches in cancer treatment79.
To use pathway-based markers in classification, we need a way to infer the activity of a given pathway based on the expression levels of the constituent genes.
(iii) All study coordinators will be trained to improve the organization of the care process by developing and implementing a care pathway, based on the evaluation of the care process and the set of evidence-based key interventions.
However, activation of HXK1 by an alternative pathway based on the transactivator VP16 moved the locus away from the nuclear periphery and abrogated the normal induction of HXK1 by galactose.
In this study, the authors propose a formal documented methodology for developing a local MRI care pathway based on the well-established nominal group technique.
The as-prepared nanostructures show the enhanced electrocatalytic activity for oxygen reduction reaction (ORR), dominated by a four-electron pathway based on the Koutecky-Levich plots, mainly owing to the inhibition of the formation of Pt OHad via the downshift of d-band center for Pt.
However, evidence was also presented that the cell uptake of CNTs was through nonendocytosis pathway based on the lack of temperature dependence and lack of inhibition from endocytosis-specific inhibitor [35, 40].
The gene score is calculated for each pathway based on the average of the pathway's individual reaction scores, which is determined by the estimated promiscuity of the putative enzyme assigned to the given reaction based on the tensor product technique.
Readmission rates remained stable throughout the study period.Implementation of an asthma care pathway based on the electronic health record improved the efficiency and variable direct costs of hospital care, reduced variability in practice, and ensured adherence to high-quality national guidelines.
To build the classifier, we evaluated each pathway based on the discriminative power of its activity score to classify samples.
