Sentence examples for pathway and development from inspiring English sources

We also showed that selection of the sensitive parental tumor SCC61 against IFNα or IFNγ led to constitutive overexpression of the IFN/STAT1 pathway and development of resistance to IR [18].

These pathological findings indicate an association between hyperactivation of the complement pathway and development of the characteristic microstructures of PIG.

When expression levels in hormone-sensitive or -refractory tumours were used to investigate a link between activation of the PI3K pathway and development of hormone-refractory disease, only AR phosphorylated at the Akt consensus site was associated with survival.

Implications for understanding potentially common etiological pathways and development of interventions designed to target multiple behaviors are discussed.

Thus, search for new signal pathways and development of new therapeutic strategies are in progress.

Given the strong enrichment of genes associated with Signalling Pathways and Development and Differentiation functions (Tables  3 and 4), we sorted DE genes according to participation in major developmental regulatory pathways.

Genetic intervention in jatropha requires understanding of the biosynthetic pathways, metabolic flux control points, cloning of the genes that code for the enzymes and proteins involved in the metabolic pathways and development of molecular markers.

Neonates and infants are particularly vulnerable because of their rapid growth, cell differentiation, immaturity of metabolic pathways, and development of vital organ systems (Eskenazi et al. 1999; Landrigan et al. 1999).

24 The study of pharmacogenetics in paediatric patients is complicated by the need to take into account differences in the ontogeny of drug metabolic pathways and development of receptors.

Since the initial characterization of a member of the insulin receptor family in E. multilocularis, EmIR1 [ 10], few studies have been conducted to investigate the effects of mammalian insulin on flatworm parasite insulin signalling pathways and development.

Individuals belonging to the same species show not only phenotypic variations that influence all biological aspects of the organism in more or less profound ways, including physiology, metabolic pathways and development, but also susceptibility to diseases.