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Duncan, L. E. et al. Pathway analyses implicate glial cells in schizophrenia.
E.M. and P.D. performed biological and clinical enrichment and pathway analyses.
J.R. and G.D.B. led the pathway analyses and generated enrichment plots.
His research also involves data mining, bioinformatics and pathway analyses, DNA/RNA secondary structure.
Enrichment and pathway analyses were performed using Panther for GO correlations, along with IPA, both with standard parameters.
Pathway analyses unravelled a significant enrichment of 'adipogenesis' genes in both control and LSD1-overexpressing adipocytes (Fig. 2c,d).
KEGG pathway analyses of these DEGs indicated that PPARα signalling pathway and fatty acid degradation pathway may be involved in the pathogenesis of APFL (Fig. 6).
The identified differentially expressed (DE) genes (fold change >1.5) were used to conduct pathway analyses by Qiagen Ingenuity Pathway Analysis (IPA) (Ingenuity Systems).
Applying toxicity and adverse outcome pathway analyses to synthetic biology is also discussed.
We also performed gene-based association tests and biological pathway analyses.
Ingenuity pathway analyses (QIAGEN bioinformatics) were used to identify targets and pathway differentially expressed between the Lgl1 WT and Lgl1 cKO samples.
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