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Acknowledging industry concerns, the F.D.A. on Tuesday proposed creating an "innovation pathway" aimed at speeding regulatory reviews of a small number of groundbreaking devices.
This is a classical example of an organism utilizing pre-existing biochemical reactions to create a novel metabolic pathway aimed at circumventing an environmental challenge.
We describe the introduction of a clinical pathway aimed to facilitate early coronary angiography and reduced length of hospital admission for patients with NSTE-ACS.
UK health policy mandates the use of a standardised cancer treatment pathway aimed at improving survival rates through reducing variability in treatment decision-making.
Development of targeted therapies has focused on mTORC1 and other components of the HIF-1 α signalling pathway, aimed at reducing the effects of growth factors, including VEGF and PDGF.
However, traditional inhibitors of the polyamine pathway aimed at these proteins have cytostatic effects with curative rates only achieved in combination with polyamine analogues in murine malaria models [ 8].
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The findings described here form a milestone in discovering novel inhibitors for the NER pathway aiming at improving the efficacy of current platinum-based therapy, by modulating the XPA ERCC1 interaction.
In 2014, the European Council set the binding EU-level target to at least 27% for the share of renewable energy consumed in the EU in 2030 [3], and Germany is trying to accelerate its energy transition pathway aiming at providing 55 to 60% of the electricity consumed from renewables by the year 2035 [4].
The two-dimensional graphical display of a pathway aims to capture the interdependencies between elements that concur to a biological function resulting from the sequential interaction of the elements.
UPR takes place in the ER lumen and is a major signal transduction pathway aiming to alleviate ER stress by removing accumulated unfolded proteins from this cellular compartment [ 18].
Thus, induction of ER stress by palmitate turns on multiple pathways aimed to attenuate protein synthesis in β-cells exposed to glucolipotoxicity.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com