Sentence examples for pathway achieves from inspiring English sources

The finding that the lysosomal pathway achieves the rapid degradation of RhoB is relevant because the proteasome is considered responsible for the degradation of most short-lived proteins [1].

The ESCRT pathway achieves receptor sorting through an elaborate division of labor.

As the Viral Function pathway achieves the highest score and is clinically relevant to CFS, we consider these 29 genes as top candidates of the standard analysis.

Next, we picked up some milestones of engineered metabolic pathway achieved in the past few years.

These findings establish that reductions in Tor-Tsc signaling also produce axon guidance defects, although quite mild in comparison to activation of the pathway achieved by loss of Tsc1 function.

For example, the activation of a signalling pathway achieved by 10 pmol of electrophile will be half that achieved by 20 pmol in the cells that are exposed to the same volume.

Data presented in Figure 3 clearly show that activation of both p38 and JNK pathway achieved by expression of c.a. mutants of the pathway members led to a significant reduction in Mss4 promoter activity.

The combination of the fatty acid biosynthetic pathway and the branched-chain amino acid biosynthetic pathway achieved a high proportion of FABCEs with improved low-temperature properties and high energy densities.

An unbiased RNAi screen for enhancers of dalotuzumab efficacy revealed that blockage of the PI3K/AKT/mTOR pathway achieved the highest synergy, and thus drugs targeting this pathway were the strongest candidates for combination therapy (Di Cosimo et al, 2010).

Premature activation of the Cdk1/Cdc5/Mus81 pathway, achieved here with phosphomimetic Mms4 variants as well as in S-phase checkpoint-deficient genetic backgrounds, induces crossover-associated chromosome translocations and precocious processing of damage-bypass SCJ intermediates.

Furthermore, increased signalling mediated by the PI3K/AKT pathway, achieved via mutations in PIK3CA or loss of PTEN expression are not mutually exclusive, suggesting that independent growth advantages are provided by these two cancer promoting changes in colorectal cancer.