Sentence examples for pathway I from inspiring English sources

Together, these data suggest CIITA has two effects on the HIV replicative cycle in producer cells, both of which are independent of the MHC II antigen processing pathway; i) it does not induce HLA-DR, mediated intracellular retention of Gag and ii) it increases the infectivity of HIV virions.

Stimulation of the Wnt/β-catenin pathway i) drastically decreased SREBP-1c protein and intramyocellular lipid deposition in myotubes; ii) increased basal glucose transport in both insulin-sensitive and insulin-resistant myotubes through a differential activation of Akt and AMPK pathways; iii) restored insulin sensitivity in insulin-resistant myotubes.

The overall barrier for pathway (i) is 14.0 kcal mol−1.

The alternative arrangement relevant for pathway (i) is seen in I a 3(i) and lies 8.7 kcal mol−1 higher in energy.

The time taken for the initial phone call, and the time taken for the anaesthetist to review the summary and follow pathway (i) or (ii) were recorded.

Comparing the values of Q i (j) between the CIN pathway (i = 1) and the MSI pathway (i = 2), it appears that the largest cancer cases is between the age group 65 and 70 years old for the CIN pathway and is between 85 and 90 years old for the MSI pathways.

The overall energy barriers of the rate determining step for the three pathways, in decreasing order, is as follows: pathway I-1 (28.41 kcal/mol) > pathway I (26.54 kcal/mol) > pathway I-2 (18.99 kcal/mol), indicating that pathway I-2 is the most favorable for formation of γ-borylated product (1 R*,3 S*)- 2 in the model reaction.

In that context, it is significant to learn that the Rh H migratory insertion pathway I-2 is favored.

(3) Of the potential pathways to the β-borylated product considered, the amide rotation pathway (pathway I-2) is calculated to be the most favorable.

The energy barrier for rotation to TS5 (7.7 kcal/mol) is roughly equal to that for adding THF as proposed in pathway I-1.

In pathway I-1, we explored a pathway in which a molecule of solvent (i.e., THF) is explicitly reintroduced into the mechanism.