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Furthermore an analysis of the paths identified by HME3M for each metabolic network confirmed known biological responses of Arabidopsis.
New paths identified by GRN expansion were validated by looking for support for the relationship in DNA binding sites and single-gene perturbation studies.
Of the two paths, the proposed method found three metabolites, Phytofluene, ζ-Carotene and Neurosporene while the extreme pathway analysis identified two metabolites, 9,9'-Di-cis- ζ-Carotene and 7,9,7',9'-Tetra-cis-lycopene, to reach Lycopene, as can be seen from Fig. 4. The paths identified by the above two methods are different till it reaches the metabolite Lycopene.
Similar(57)
It is then followed by the beta path identified by the models' sequence (16b).
Then we chose another substrate which also belongs to the path identified by us but this time the substrate could lead to various branches, of which one would eventually lead us to the target.
Constrained maximum-capacity paths are identified by iteratively using a revised shortest-path algorithm.
Key shortest paths were identified by considering direct connections between the target genes, paths in which the target genes themselves acted as inter-connectors, and the most frequently occurring genes providing internal linkages.
In more details, each path is identified by a path ID to which the CIDs are bound.
Optical paths are identified by their wavelengths.
Paths were identified by the existence of a correlation between items after taking account of the underlying latent characteristic.
For assessing the consistency, we display this aggregation step in a forest plot where each row represents a path-based effect estimate and each path is identified by its unique list of intermediate treatments.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com