Exact(1)
As patients progress to severe dementia, the burden of tau pathology rises to peak levels (5).
Similar(59)
Atherosclerosis, the most significant pathology giving rise to CHD, is characterised by a thickening of the artery wall [15].
The birth of bacteriology as a separate discipline of pathology gave rise to the introduction of the important description of microbiology in the etiology of infective endocarditis.
Altogether, these results suggest that DUX4 expression per se is not sufficient for FSHD muscle pathology and rise the possibility that additional factors might contribute with DUX4 leading to disease progression.
Although IBD predominantly affects people in the Western world (e.g. Europe and North America), both the incidence and the prevalence of this pathology have risen in Asia, especially in areas that have adopted an industrialized lifestyle (Ng et al., 2012; Prideaux et al., 2012).
Management of hearing loss requires a thorough understanding of the pathophysiological mechanisms through which diverse pathologies give rise to hearing impairment in humans.
These pathologies give rise to increased levels of extracellular adenine nucleotides which, through the activation of a variety of cell surface P2 purinergic receptors, influence the inflammatory activities of responding immune cells.
The positive PCR-RLB results were supported in all but 1 case, with pathology results giving rise to suspicion of infection.
Sir, The article by Bowen et al (2008a), reporting that Black women in Hackney presented for breast cancer at a median age of 21 years younger than that of White women and had more serious pathology, has given rise to widespread concern and a petition to 10 Downing Street calling for a programme of early breast cancer screening for Black women.
These disorders tend to give rise to pathology in tissues that are reliant on absolute mitochondrial function, in particular oxidative phosphorylation and with little capacity to upregulate compensatory increases in glycolysis, suggesting a direct correlation between efficient energy production and mitochondrial function.
An understanding of the cellular defects in CDG that give rise to pathology are particularly relevant to the broader field of liver disease, because non-alcoholic fatty liver disease, fibrosis and cirrhosis have all been associated with defects in protein glycosylation (Blomme et al., 2009).
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