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From the microbiota side, there is big room to study molecular genetics mechanisms by which how the physiology and pathology relevant microbiota taxonomic and functional profiles are regulated.
Students were specifically trained to assess for pathology relevant in the immediate emergency care of patients.
General health was good in all patients without any pathology relevant to the loss of visual performances.
We determined here the extent to which the cholesterol-fed rabbit model for AD also exhibits retinal pathology relevant to AMD.
An animal model of synuclein pathology relevant to Parkinson's disease was used to determine whether age-related loss of the activity of the identified group of neurons is associated with changes in ventricular electrophysiology.
The NOSGER is a rating scale that covers a wide range of behavioral pathology relevant to daily functioning and independent of gender or social status of the patients [ 70].
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Consequently, GDABMP therapy may provide a novel treatment for PD that addresses multiple pathologies relevant to this disease, but also are likely to be equally useful for treatment of other neurodegenerative diseases.
Gene targeting in embryonic stem (ES) cells allows virtually unrestricted manipulation of the mouse genome, including the engineering of large segmental aneuploidies (Liu et al, 1998; Ramirez-Solis et al, 1995) and many pathologies relevant to human disease can be induced in the mouse using environmental, pharmacological or genetic sensitization protocols.
Altered FA has been previously shown in brainstem nuclei in the presence of known neuronal loss, including altered FA in the SN in Parkinson's Disease [e.g. [65], [66]], confirming the potential for FA to detect pathology-relevant changes in the VTA/SN region.
The different meta-analysis methods all aimed to identify pathology-relevant gene expression, and concordance at the pathway level offered a degree of cross-validation.
Standardised pathology-relevant parameters of dystrophic muscle in mdx mice for histological analysis have been developed in international, collaborative efforts, but automation has not been accessible to most research groups.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com