Sentence examples for pathology phenotyping from inspiring English sources

The use of standardised nomenclature for lesions, based on accepted ontologies such as the mammalian pathology ontology (MPATH) (Schofield et al., 2010a), should be an absolute requirement for data capture from high-throughput pathology phenotyping.

Taken together, findings in lines with mutations in orthologous genes indicate that clinical and pathology phenotyping yield both complementary and unique phenotype annotations for a complete and enriched characterization of mouse models of human disease.

Nowadays, gene expression profiling should be considered as an adjunct to high-quality pathology phenotyping which results in an indication of certain therapies for early breast cancer patients [ 29] that contain Aurora A as one of the proliferation-genes.

Metabolomics, generally defined as the measurement of all metabolites in a given system under particular conditions [ 45], is a key functional genomics tool with widespread applications ranging from genotype discrimination to pathology phenotyping and natural product discovery.

The Panel considered the available multigene assays in this context and concluded that a validated assay should be taken into account as an adjunct to high-quality pathology phenotyping if doubt about the indication for chemotherapy persists after consideration of other factors.

Aerts... [et al.] -- PKU in Turkey : screening, diagnosis, and management / Hulya Gokmen-Ozel and Turgay Copkun -- Phenylketonuria and therapeutic approaches / Erin L. MacLeod and Denise M. Ney -- Canavan disease : molecular pathology, phenotype, and therapeutic approaches / Sankar Surendran, Namik Kaya, and Pinar Ozand.

The experimental model here presented was established in non-immune mice, which enhanced disease severity and magnified pathology phenotypes as compared to the human disease.

In some lines, multiple pathology phenotypes were observed, consistent with multiple clinical phenotype hits.

Linkage is shown significantly for the CAD phenotype, the stroke/TIA phenotype and the macrovascular pathology phenotype and with a less significant empirical P-value with the vasculopathy phenotype.

The finding of abnormalities unrelated to clinical phenotypes illustrates that important pathology phenotypes will be missed if histopathology is restricted to perceived target organs or tissues based on clinical phenotyping.

In 17 of these lines, histopathology revealed an unequivocal pathology phenotype that potentially explained at least one documented clinical phenotype, and added morphologically and biologically relevant information to the phenotype annotation.