Sentence examples for pathology phenotype from inspiring English sources

Aerts... [et al.] -- PKU in Turkey : screening, diagnosis, and management / Hulya Gokmen-Ozel and Turgay Copkun -- Phenylketonuria and therapeutic approaches / Erin L. MacLeod and Denise M. Ney -- Canavan disease : molecular pathology, phenotype, and therapeutic approaches / Sankar Surendran, Namik Kaya, and Pinar Ozand.

Linkage is shown significantly for the CAD phenotype, the stroke/TIA phenotype and the macrovascular pathology phenotype and with a less significant empirical P-value with the vasculopathy phenotype.

In 17 of these lines, histopathology revealed an unequivocal pathology phenotype that potentially explained at least one documented clinical phenotype, and added morphologically and biologically relevant information to the phenotype annotation.

From studies of the proportions of different types of PrPd accumulation (the PrPd profile), we have proposed that the pathology phenotype of sheep strains are partly the result of differences in the relative affinity of different sheep scrapie agents for different cell types and by differences in the cellular processing of PrPd(15).

The experimental model here presented was established in non-immune mice, which enhanced disease severity and magnified pathology phenotypes as compared to the human disease.

In some lines, multiple pathology phenotypes were observed, consistent with multiple clinical phenotype hits.

The finding of abnormalities unrelated to clinical phenotypes illustrates that important pathology phenotypes will be missed if histopathology is restricted to perceived target organs or tissues based on clinical phenotyping.

The use of standardised nomenclature for lesions, based on accepted ontologies such as the mammalian pathology ontology (MPATH) (Schofield et al., 2010a), should be an absolute requirement for data capture from high-throughput pathology phenotyping.

Taken together, findings in lines with mutations in orthologous genes indicate that clinical and pathology phenotyping yield both complementary and unique phenotype annotations for a complete and enriched characterization of mouse models of human disease.

However, we think it is important to take in consideration that the linkage signal detected for the macrovascular pathology phenotypes in our study may indeed reflect the underlying linkage for T2D [ 5].

The translation of these into model mice by treatment with a novel, orally available drug, indicates that strength and pathology phenotypes can be improved by treatment without overt hormonal, growth or immunosuppressive effects.