Such systems for 3D culture would be particularly useful for studying 3D biological phenomena, such as the organization and pathology of tissues, or the metabolism and distribution of drugs.
Previously, it was postulated that the failure of current treatments such as cyclodextrin (CYCLO) to correct the pathology of tissues such as the lung was due to the inability of CYCLO to reach lung macrophages (27, 34).
As CCN2 plays roles in connective tissue pathologies, targeting Ets-1 may be beneficial in alleviating pathologies of tissue remodeling and repair, including cancer, arthritis and fibrosis.
The advent of reliable cell culture techniques raised hopes that tissue engineering might be able to cure any type of cartilage damage, regardless of pathology, degeneration of tissue, health status and age of patient [ 13].
A limitation in our understanding of epithelial tissue and tumors that are derived from them is that most insight into the formation, maintenance, function and pathology of epithelial tissue has depended on the analysis of traditional 2D cell tissue culture.
JC collected the tissue specimens and the clinical data, examined the pathology of the tissue, and prepared the pathology reports.
Tissues were harvested within 30 min after complete resection, and the quality and pathology of tumour tissue was confirmed by the study pathologist (M-ST).
Pigmented villonodular synovitis (PVNS) is a rare, locally aggressive benign proliferative pathology of synovial tissue.
Moreover, different molecular mechanisms seem to underlie the opposite changes in GLCE expression in the benign and malignant pathology of prostate tissue.
