Sentence examples for pathology load from inspiring English sources

Furthermore, synaptic density measurements can be compared with intrinsic pathology load to assess whether an inverse correlation exists or whether synapse loss is independent of detectible pathology.

In contrast, there was no correlation between in vivo PiB DVR values and the neurofibrillary pathology load as revealed by AT8 IHC (Fig. 6C).

This may be due to different sets of functional variants residing in the same haplotypic backbone and leading to different biological outcomes resulting either in a primary tauopathy vs. tau pathology in LOAD; a more complex genetic architecture in LOAD with contribution from multiple functional variants in different pathways; or a combination of both.

Triggering of growth-plate cartilage pathology by loading the ER with misfolded transgenic mutant proteins (type X collagen, matrilin-3) first illustrated chondral effects of excess UPR activation [ 11, 12].

All the monkeys with latent TB co-infected with SIV experienced clinical signs, pathology and bacterial load consistent with reactivated disease while the Mtb-negative SIV-infected monkeys did not develop simian AIDS or opportunistic infections within 11 months of infection.

The similarities between EOAD and LOAD pathology are integral to the amyloid hypothesis.

In these studies, cardiac pathology and viral load were correlated, with an up regulation of T cell response genes.

Peak of cardiac pathology and viral load coincided with cardiac-specific upregulation of T cell response genes and splenic induction of complement genes.

In cognitively impaired subjects, the American National Adult Reading Test and all biomarkers of neuronal pathology and amyloid load were independently correlated with all cognitive measures.

However, the majority of genes showed highest upregulation in heart at peak pathology and viral load, 8 and 9 weeks after infection, indicating their role in B cell responses and presentation of viral antigens to effector T cells.

It was shown that the peak of cardiac pathology and viral load coincided with a cardiac-specific induction of T cell response genes and splenic induction of complement genes.