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Eventually a classification based on the reason the patient consulted emerged to replace that based on pathology defined disease.
Eosinophilic esophagitis (EE) is a recent pathology defined by abnormal immune response of the esophageal mucosa to exogenous allergens, leading to chronic mucosa infiltration by 15 eosinophils per High-Power-Field (Eos/HPF).
More importantly, this molecular shift is observed in 3-weeks old mice, before the main features of Tau pathology, defined by the appearance of abnormal and hyperphosphorylated Tau aggregates, that occurs in 6 to 10 months-old mice.
All patients included in our present study had synovial pathology defined by synovial hypertrophy visualised on US scans.
For in instance, in AD, the hierarchical spreading of Tau pathology, defined by the Braak stages, may last for 20 years [ 6].
Classic pathology defined any sarcoma with fibroblasts a fibrosarcoma, and as a result the diagnosis "fibrosarcoma" represented two-thirds or more of all sarcomas diagnoses.
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IL-1-driven pathology defines a new emerging family of diseases classified as autoinflammatory.
With the aim of describing the prevalence of chronic diseases and multimorbidity, we adopted a list of 47 pathologies, defined by consensus among the research team.
The AUC for the ROC curves of the composite scale comprising all three joint pathologies defined by RAMRIS was highest in every joint area, indicating that both damage and inflammation contributed with relevant information for the correct classification of the individuals.
While defining the relationship between tissue events and pain is necessary for understanding the clinical context of these pathologies, defining the relationship between injury and specific and relevant nociceptive responses is crucial for understanding the central mechanisms of persistent pain in FM.
Serious pathology is defined as pathology requiring treatment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com