Sentence examples for pathological signature from inspiring English sources

Endoplasmic reticulum (ER) stress is a common pathological signature of a variety of diseases, which engages the unfolded protein response (UPR) as a cellular reaction to mitigate ER stress.

Early age lens cataract is a significant pathological signature of Danish dementia [8].

Besides the accumulation of soluble and insoluble Aβ, the intraneuronal abundance of hyperphosphorylated filamentous tau protein represents the second major pathological signature of AD [32] [34], which correlates well with cognitive impairment [35], [36].

A characteristic white matter tract pathological signature is seen cross-sectionally, while cortical involvement dominates longitudinally.

Macrophages are a key pathological signature of AMD (Jager, 2014; Killingsworth et al., 1990; Seregard et al., 1994).

Dermal lymph emboli on skin biopsy are a pathological signature of IBC, and are generally associated with clinical inflammatory signs.

Based on their pathological signatures, AD and PD can be considered as two different disease entities.

Complex phenotypes (e.g. disease syndromes or pathological signatures) usually consist of a large number of quantitative traits such as clinical and molecular (e.g. gene expression) signals.

Quantitative characterization based on morphometric analysis of histological placental images has been performed to identify significant pathological signatures of preeclamptic placentae.

Because mutations in any of the three CCM genes lead to the onset of similar pathological signatures, the three CCM proteins likely share a common mechanism of action.

L31/CD4-/ mice mimic most parts of clinical and pathological signatures of GBS in human; thus providing an unconventional opportunity to experimentally explore the critical events that lead to spontaneous, autoimmune demyelinating disease of the peripheral nervous system.