Sentence examples for pathological signalling from inspiring English sources

Pathological signalling in AD is largely mediated by two major characteristic components, neurofibrillary tangles and senile plaques (Gomez-Isla et al., 1997).

In this article, we highlight ECM remodelling as an integral part of directional pathological signalling in IBD rather than, as is often considered, a passive bystander.

Activation of the receptor can occur at the site of lesion by ATP leaking from degenerating cells (Ferrari et al, 1997) or, distantly from the lesion, through propagation of ATP-mediated Ca2+ wave among astrocytes, a process that has a function in pathological signalling events (Nedergaard et al, 2003).

The diversity of physiological and pathological signaling outcomes produced by PA is still a mystery, due mainly to the inability to visualize the dynamics of its production within cells.

We took advantage of the AKAP-Lbc RhoA complex crystAKAP-Lbc RhoAto design in silicomplexl molecrystalredicted to inhibit the astructure patoological signaling cascadesign

In addition, preoperative enhancements in muscle health with corresponding benefits in overall fitness, BFR induced molecular alterations could also be able to interfere with TKA induced pathological signaling.

Thus, pathological signaling (as well as trafficking and internalization) of receptors may be initiated by their incorrect dimerization depending on direct or indirect (via adaptor proteins) receptor receptor interactions, leading to neuroinflammatory responses.

Indeed, impacts of diseased microenvironments on MSC function rely not only on the dynamic regulation of resident MSCs by surrounding niche to convoy pathological signals of bone, but also on the profound interplay between transplanted MSCs and recipient components that mediates and modulates therapeutic effects on skeletal conditions.

My project seeks to identify key components in the pathological signaling pathway induced by alterations in the mechanical microenvironment observed during atherosclerotic development.

Zheng et al. [63] carried out pathological signal detection based on DWT, MFCC, and dynamic time warping (DTW).

The maximum classification accuracy rate of 98.6% is achieved with 50 signals of 51 normal and 159 out of 161 pathological signals are correctly classified.