Sentence examples for pathological signaling from inspiring English sources

In addition, preoperative enhancements in muscle health with corresponding benefits in overall fitness, BFR induced molecular alterations could also be able to interfere with TKA induced pathological signaling.

A third conclusion is that Sho may open a window to pathological signaling events in prion disease.

ROS also affects nitric oxide (NO) that in contact with superoxide generates highly reactive peroxynitrite (ONOO-), which induces cascade of pathological signaling.

While the physiological signaling of insulin in insulin-sensitive subjects is mediated through the phosphatidylinositol-3-kinase signaling pathway resulting in the release of nitric oxide (NO) and vasodilation, pathological signaling through the mitogen-activated-protein-kinase signaling pathway in insulin-resistant subjects stimulates endothelin 1 release with subsequent vasoconstriction [ 26].

We took advantage of the AKAP-Lbc RhoA complex crystAKAP-Lbc RhoAto design in silicomplexl molecrystalredicted to inhibit the astructure patoological signaling cascadesign

Pharmaceutical research has increasingly relied on reductionist approaches, even though systemic diseases such as cancer and heart disease are managed by large, interconnected networks with many pathways affecting pathological signaling [4,5].

Zheng et al. [63] carried out pathological signal detection based on DWT, MFCC, and dynamic time warping (DTW).

The maximum classification accuracy rate of 98.6% is achieved with 50 signals of 51 normal and 159 out of 161 pathological signals are correctly classified.

For example, in pathological speech recognition, while the nature of both normal and pathological signals is speech, only few high-frequency contents or transient components cause the discrimination between the two classes.

The alar ligament system is involved during cervical extension, lateral flexion, and ipsilateral rotation; nevertheless we found no correlation between side location of pathological signal intensity (higher signal intensity) in the ligaments and the side location of the CEH [16, 17].

Indeed, impacts of diseased microenvironments on MSC function rely not only on the dynamic regulation of resident MSCs by surrounding niche to convoy pathological signals of bone, but also on the profound interplay between transplanted MSCs and recipient components that mediates and modulates therapeutic effects on skeletal conditions.