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This high diversity is believed to maintain the enteric flora and to protect from overgrowth of indigenous or exogenous pathological microbes [ 13, 11].
It is caused by increased numbers of Streptococcus mutans and other pathological microbes in the biofilm, decreased pH and compromised oral hygiene [ 3].
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Yang et al.[ 13] have applied an ensemble clustering framework to delineate the structure of human microbiome and provide a new insight to the pathological role of microbes within the host organism.
As is the case for all psychiatric disorders, the diagnosis of attention deficit hyperactivity disorder (ADHD) is not based on a specific pathological agent, such as a microbe, a toxin, or a genetic mutation, but rather on the collection of signs and symptoms and evidence of impairment that occur together more frequently than expected by chance (Todd et al. 2005).
The GBPs can stimulate caspase-11-dependent pyroptosis, a specific form of apoptosis triggered by pathological stimuli such as contact with microbes, toxins or viruses [ 5].
Additionally, the pathological findings of the vegetation were negative for microbes, which suggested that the combination regimen was highly effective in biofilm penetration and killing the bacteria.
These normal lung defense mechanisms ensure that most host-microbe interactions do not lead to persistent pathological consequences.
It is most commonly defined as a pathological state characterized by the loss of normal vaginal flora, particularly Lactobacillus species, and overgrowth of other microbes including Gardnerella vaginalis, Bacteroides species, Mobiluncus species, and Mycoplasma hominis.
In addition to impaired clearance of microbes, impaired phagocytosis can cause insufficient clearance of dying or dead cells and lead to pathological inflammation.
The stress conditions including nutrient starvation, hypoxia conditions, invading microbes, and tumor formation, have been shown to induce autophagy that allows cell survival in these stressful or pathological situations.
Deadly microbes?
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