Sentence examples for pathological inflammatory from inspiring English sources

However, loss of RIPK1 sensitizes macrophages to activate RIPK3 in response to inflammatory stimuli, thereby exacerbating a potentially pathological inflammatory response.

Elucidating these RIPK1-dependent regulatory pathways may open new therapeutic strategies against chronic pathological inflammatory diseases in which proinflammatory priming of macrophages is a distinctive feature.

FPR2-specific interaction can be possibly used to facilitate the resolution of pathological inflammatory responses by enhancing endogenous anti-inflammation systems.

N-Formyl peptide receptors (FPRs) are G protein-coupled receptors (GPCRs) that play critical roles in inflammatory reactions, and FPR-specific interactions can possibly be used to facilitate the resolution of pathological inflammatory reactions.

Rats denervated of primary afferent fibers with neonatal capsaicin injection and animals pretreated with a nonpeptide SPR antagonist showed few endosomal SPRs, and the pathological inflammatory effects of toxin A were ablated.

This leads to "endothelial dysfunction" with a reduction in endothelium-dependent vasodilation and the induction of a specific state of "endothelial activation," characterized by a proinflammatory, proliferative, and procoagulatory milieu which favors all stages of atherogenesis, pathological inflammatory processes, and vascular disease [14].

Enterocolitis in oncology patients remains an important complication, but there is a lack of insight into its likely severity from microbial, pathological and inflammatory aspects.

We addressed causative links between the biochemical, pathological and inflammatory disorders in a mouse model of this disease.

In contrast, transection of the spinal cord results in a narrow zone of primary tissue damage that is followed by a focal secondary pathological and inflammatory response [97].

Patients that had CNV secondary to pathological myopia, inflammatory disease, angioid streaks or trauma were excluded from this study.

Since mPGES is induced in cartilage in pathological and inflammatory conditions [ 13, 17] we probed the membranes with antibodies against the protein.