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Among malignant masses, greater size correlates with higher pathological grade [4, 22, 23, 24].
Several studies observed that the expression of TAZ in tongue squamous cell carcinoma significantly correlated with tumor size, pathological grade, and clinical stage.
These pathological changes were considered to be induced by chemotherapy, and the pathological grade was determined to be grade 2a (Fig. 7).
However, it is positively associated with the size of tumor (P < 0.05), pathological grade (P < 0.05), and TNM stage (P < 0.05).
As the pathological grade of meningioma increased, the positive rates of E-cadherin and β-catenin in meningioma decreased.
In the original VPNI [6] three independent histo-pathological parameters of relapse were considered: tumor size, margin width and pathological grade.
Next, a pathologist classified each biopsy according to the worst pathological grade; in cases where a biopsy and surgical specimen were obtained, the worst pathological grade was selected.
The Mann-Whitney test was used for pathological grade and clinical stage ranked data analysis.
Clinically, cancer cells with a poor differentiated pathological grade usually have a worse therapeutic response [ 22].
Thus, pathological grade was the only independent factor in the bladder cancer survival.
As representative prognostic markers, pathological grade and tumour stage are very useful.
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