Sentence examples for pathological cells from inspiring English sources

Our current understanding of membrane lipid composition, structure and functions has led to the investigation of their role in cell signaling, both in healthy and pathological cells.

Hyperthermia: Placing superparamagnetic iron oxide in altering current [AC] magnetic fields randomly flips the magnetization direction between the parallel and antiparallel orientations, allowing the transfer of magnetic energy to the particles in the form of heat, a property that can be used in vivo to increase the temperature of tumor tissues to destroy the pathological cells by hyperthermia.

Samples containing more than 60% of blasts were chosen in order to analyze a majority of pathological cells.

Our data indicate that IPF myofibroblasts are intrinsically pathological cells with fundamental changes in their gene expression pathway primarily at the level of ribosome recruitment regulation.

Specifically, we sought to test if the disorganized cells filling the barbel core were "stem-like", capable of further proliferation and differentiation, or "scar-like", similar to pathological cells filling up a wound.

In general, these molecules recognize the programmed apoptosis protein receptors presented on the surface of aging or pathological cells, activate a series of intracellular signal transduction pathways and eventually lead to cell death.

Nikonova, A. S., Astsaturov, I., Serebriiskii, I. G., Dunbrack, R. L. Jr. & Golemis, E. A. Aurora A kinase (AURKA) in normal and pathological cell division.

These compounds have been employed to dissect the lethal mechanism and implicate this process in pathological cell death events observed in many tissues, including the brain.

Background context: Biological and pathological cell processes during the degeneration of intervertebral discs are as yet poorly understood.

Conversely, a number of small molecule inhibitors of ferroptosis have been identified, including ferrostatin-1 and liproxstatin-1, which can block pathological cell death events in brain, kidney and other tissues.

Here we review the diverse mechanisms cells use to adapt metabolism to specific physiological states and discuss how metabolic flux analyses can be applied to identify important regulatory nodes to understand normal and pathological cell physiology.