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Complete pathologic responses are rare, however, and the benefits of this approach compared with standard adjuvant therapy are uncertain.
Allergic asthma is characterized by a failure of immune tolerance and the development of pathologic responses to inhaled aeroallergens, and vitamin D has been extensively shown to support immune regulation.
This study was designed to assess the relationship between local hemodynamics and pathologic responses of the distal anastomosis by manipulation of the angle of anastomosis of the graft, a major determinant of local hemodynamics.
For example, frequent invasive sampling of tumor tissue was required to demonstrate that increases in apoptotic index predicted pathologic responses of breast cancer to neoadjuvant chemotherapy [25], [26].
PAF is a phospholipid cytokine implicated in a wide range of biological and pathologic responses [1], and thus, the different responses of pPAF-AH, the regulator of serum PAF [6], between sepsis patients and LPS models of Syrian hamster, rat and mouse (Table 2 and Figure 1) might be accounted by the differences in the profile of cytokine release.
Pathologic responses were scored by a pathologist.
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Surgical pathology revealed a complete pathologic response.
Five current pathological classification systems were applied retrospectively to assess pathologic response after neoadjuvant chemotherapy.
For patients who received only Herceptin and taxotere, only 21.5 percent had a complete pathologic response.
Complete pathologic response.
In contrast, major pathologic response was achieved in the current case treated with alectinib.
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