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Pathogens can cause necrosis by secreting a toxin (poison).
All of these pathogens can cause primary skin and soft tissue infection [8, 31, 32].
Many genotypes of the enterovirus (EV) pathogens can cause clinical hand-foot-and-mouth disease (HFMD).
However, in certain conditions, some microbes composing our microbiota generically called opportunistic pathogens can cause serious infections mainly by regulating their virulence [1, 2].
In the criminal justice system, jails and prisons are the most obvious reservoir: In their confines, many air-, food-, and blood-borne pathogens can cause fatal infectious diseases such as HCV, HIV/AIDS, STD and TB.
Although most EV and HPeV infections remain asymptomatic, both pathogens can cause a wide spectrum of clinical manifestations ranging from respiratory or gastrointestinal symptoms to myocarditis, neonatal sepsis, and infections of the central nervous system.
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Whether or not a pathogen can cause an infection depends on the balance between pathogenic expansion and microbiome homeostasis, which has been extensively studied in murine models [17].
Vibrio cholerae, a food-borne pathogen, can cause epidemics of cholera in human through the condition of acute watery diarrhoea.
A hydrophila, an uncommon human pathogen, can cause invasive infections in immunocompromised individuals and common clinical presentations in acute gastrointestinal illness, soft-tissue infections and sepsis.
Although the pathogen can cause severe illness, such as meningitis, a healthy person's immune system can usually destroy it before any damage is done.
This fungal pathogen can cause coccidioidomycosis, a serious infection in humans and animals.
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