Sentence examples for pathogenicity assessment from inspiring English sources

For pathogenicity assessment, mycelia cultured in CM liquid medium for 2 days were harvested (5,000×g, 2 min), washed twice with distilled water, and fragmented into the length of 30 50 µm using a homogenizer.

The pathogenicity assessment was performed using the injection method on sixth-instar G. mellonella larvae.

On the other hand, when performing extensive mutation analyses, problems with pathogenicity assessment can occur for some types of mutations.

However, in silico predictions are not always consistent with functional studies and, despite recent advances, pathogenicity assessment remains challenging, particularly for hypomorphic, synonymous and non-coding variants.

This finding is particularly important for genetic counselling in HNPCC, where the pathogenicity assessment of any nucleotide substitution is crucial to correctly predict cancer risk.

Pathogenicity assessment is based on family co-segregation, functional predictions, the degree of conservation of amino-acids and also on the analysis of precise phenotypical descriptions [ 1, 13, 14].

Pathogenicity assessments were based on molecular analysis of the H5 cleavage site by either rRT-PCR (10 ) or sequencing (11 ).

For nonsynonymous mutations, we assessed evolutionary conservation, and employed previously described pathogenicity score assessment tools.

Since we were not able to collect enough spores from the ΔMovam7 mutant for traditional assessment of pathogenicity, we collected mycelia and fragmented them before inoculation on the leaves of susceptible rice cultivar CO-39.

Assessment of pathogenicity of genetic variants remains a major challenge (MacArthur et al. 2014).

Heterozygous PARK2 variants have also been observed in healthy control individuals, making assessment of pathogenicity for these variants quite complex.