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While a leading role has been so far attributed solely to Influenza A as the primary infective pathogen, Influenza B is generally considered to be less pathogenic with little impact on morbidity and mortality of otherwise healthy adults.
It is highly non-specific and frequently pathogenic with regard to paratenic hosts, which contact eggs of B. procyonis at raccoon latrines.
Interestingly, all the variants found and considered by the authors as pathogenic, with the exception of D169G in exon 4, are situated in exon 6; all non-synonymous but benign variants identified by us, lie outside of this exon.
Variants were classified as "probably pathogenic" with a score of ≥11 points but lacking evidence from a "gold-standard" investigation, "possibly pathogenic" with a score of 7 10 points and a "neutral polymorphism" with a score of ≤6 points.
In its native host this parasite is minimally pathogenic, with a small adult body mass and low infection intensity [ 13].
Those previously reported as pathogenic with functional evidence were then sent for confirmatory testing using a diagnostic grade assay.
Similar(37)
The majority of HIV-infected children were colonized with pathogenic organisms, with high levels of antibiotic resistance.
With this approach, the 7 Enterobacteriaceae were now separated into pathogenic and non-pathogenic, with 5 falling into the first category and 2 into the latter.
Some other variants are probably non-pathogenic, with odds of >100 1 in favor of neutrality according to multifactorial model by Easton et al. [ 44].
This is particularly an issue when dealing with non pathogenic organisms with which there may also be considerable microdiversity in the sample or habitat [ 3, 31].
Sepsis is a blood stream infection usually caused by pathogenic bacteria with the diagnosis often beginning with clinical suspicion [ 3].
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