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The fact that several receptors may be involved in pathogen recognition renders the system more robust against immune evasion by the pathogenic microbe.
For a healthy subject, gut microbiota homeostasis is maintained with pathogenic microbe growth under control.
Because of the pathogenic microbe resistances to the conventional antibiotics, the calls for the investigations on new antimicrobials metabolites have been increased.
Researchers around the world are about to get their first detailed look at the genetic blueprint of a pathogenic microbe that causes most peptic ulcers.
SCFAs can be used to feed colonocyte, maintain gut barrier and inhibit pathogenic microbe proliferation due to acidic pH condition (Hashemi et al., 2017; Cherrington et al., 1991; Prohaszka et al., 1990; Duncan et al., 2009; Manrique Vergara and Gonzalez Sanchez, 2017).
Another well-studied system is the eukaryotic parasite Toxoplasma gondii, where limited mating among clonal lineages is hypothesized to have resulted in increased virulence, and may also have enabled this pathogenic microbe to be orally transmitted from animals to humans [59], [60].
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Sequence data enable powerful reconstruction of pathogen transmission chains, phylogenies, and GWAS for cultivable pathogenic microbes.
This study provides genomic-level evidence that invasiveness of pathogenic microbes can be attained without the high levels of pathogenicity presumed to exist for pathogens challenging naïve hosts.
Working against pathogenic microbes is not simple altruism.
Disinfection, usually the final step in the treatment of drinking water, destroys pathogenic microbes.
On rare occasions, dietary supplements may be adulterated with prescription medications or contaminated with heavy metals or pathogenic microbes.
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