Exact(1)
Note also that pathogenic indications in MITOMAP have to be considered with caution given the large amount of false positives in the literature and recorded in MITOMAP (see [20], [21]).
Similar(59)
Although these approaches can be used for evaluating variants found in healthy individuals or secondary to the indication for testing, further caution must be employed as noted in several parts of the guideline given the low prior likelihood that most variants unrelated to the indication are pathogenic.
Thus, the presence of hnRNP-A2 auoreactive T cells in healthy controls by itself was not surprising; a striking difference, however, was the significantly higher strength of the cellular immune response observed in SLE patients, which may be considered an indication for pathogenic involvement of these autoreactive cells and/or a lack of counter-regulation in SLE patients.
It had no external indications of past pathogenic infection, trauma or unfavourable environmental conditions.
With these findings, this study showed that amoebae can be grown at 32°C and/or 37°C giving important indications of the pathogenic potential of these organisms.
In short, conservation analysis, substitution evaluation and a tolerance test lack any indication of a pathogenic contribution from this allele.
Although this is a highly conserved residue across mammals, there is no indication this mutation is pathogenic, and the individual was considered to have been correctly identified as a true healthy control.
The considerable sequence divergence of the viruses described herein from pathogenic viruses (Table 2) gives no indication that these penguin viruses pose an imminent threat to the health of humans or live stock.
A biomarker is defined as a characteristic that can be objectively measured and evaluated as an indication of normal or pathogenic processes or pharmacological responses to a therapeutic intervention [ 4, 5].
No indications for the presence of pathogenic species were found.
The presence of faecal coliforms in drinking water may affect human health in many ways and it is an indication of the presence of pathogenic bacteria (Mintz et al. 1995).
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