Sentence examples for pathogenic hypothesis from inspiring English sources

The best model for testing the pathogenic hypothesis on Baló's sclerosis would be the experimental allergic encephalomyelitis of the common marmoset, where concentric lesions with high oligodendrocyte depletion and massive macrophage recruitment are reported [21].

It is interesting to consider these results in light of the pathogenic hypothesis.

A major pathogenic hypothesis is that SLE involves defective renal clearance of immune complexes.

Although disease may later manifest in this participant, we have yet to discover a case of unexpected disease in which the causal variant's pathogenic hypothesis lacked statistical significance.

Given the above, one pathogenic hypothesis in PsA is that molecules encoded by certain HLA class 1 alleles bind self-peptides derived from proteins found in entheseal and synovial sites.

We found that the expression of hypoxic response genes such as Hif-1 α and CaIX is greater in tumours associated with a pseudohypoxic aetiology (Cluster 1) in contrast to those associated with mTOR dysregulation (Cluster 2), consistent with the 'cluster' pathogenic hypothesis (Nolting & Grossman, 2012).

For many centuries, multiple rather enigmatic pathogenic hypotheses have been postulated, none of which satisfactorily explains their pathogenesis and conjunctional morphology.

Different studies have investigated the pathological significance of WM lesions and the pattern of their distribution, to speculate on possible pathogenic hypotheses and indicate a specific imaging marker of the disease.

The two main pathogenic hypotheses are the vascular steal hypothesis and the defective blastogenesis hypothesis.

Clinical studies of sirenomelia have given rise to two main pathogenic hypotheses.

Proposed pathogenic hypotheses for peripartum cardiomyopathy include viral myocarditis, auto-immune-mediated injury, and prolonged tocolysis.